Medicago has started recruiting participants for the Phase 3 trial of its COVID-19 vaccine candidate. (Medicago)

Medicago has started recruiting participants for the Phase 3 trial of its COVID-19 vaccine candidate. (Medicago)

Canadian company starts Phase 3 of plant-derived COVID-19 vaccine clinical trials

Feds have agreement to buy up to 76 million doses of the vaccine if it is approved

A Quebec-based biopharmaceutical company is beginning to recruit participants for its Phase 3 trial of a plant-derived COVID-19 vaccine.

In a Tuesday (March 16) news release, Medicago said that it had received approval from Canadian and U.S. regulators to begin enrolling adults into the Phase 3 portion of its trials based on positive interim Phase 2 results. That portion of the trial is almost complete, with results expected to be available publicly in April.

In parallel with the Phase 3 trial, Medicago said it has also started a feasibility study of a vaccine candidate to address emerging variants of concern.

The Canadian company is also partnering with GlaxoSmithKline, which is testing its vaccine adjuvant technology. According to the U.K.-based GlaxoSmithKline, the use of an adjuvant may reduce the amount of vaccine protein required per dose.

“We are pleased to take the significant step of initiating the Phase 3 clinical trial at sites around the world,” said Takashi Nagao, CEO and president of Medicago. “This brings us one step closer to delivering an important new COVID-19 vaccine and contributing to the global fight against the pandemic along with our partner GSK.”

Phase 3 of Medicago’s vaccine trials will enrol up to 30,000 healthy adults between the ages of 18 and 65, followed by adults over the age of 65 and adults with comorbidities. The trial will take place across 10 countries, starting with Canada and the U.S., and seeks to enrol men and women from racially diverse populations.

Ottawa has signed a deal with Medicago to secure the rights to buy 76 million doses of its vaccine. The federal government has also pledged $173 million for the company’s vaccine research and development and for the construction of its Quebec City manufacturing facility.

According to federal government data, just over five per cent of Canadians have received their first dose of a COVID-19 vaccine as of March 6.

READ MORE: Canadian company reports promising early Phase 1 test results of possible COVID-19 vaccine

READ MORE: Public Health Agency of Canada budgets $5B for COVID-19 vaccines, treatments


@katslepian

katya.slepian@bpdigital.ca

Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Just Posted

Michelle Jacobs receives her first dose of the COVID-19 vaccine at the Coast Capri Hotel on April 28, 2021. The pop-up clinic was hosted by the First Nations Health Authority. (Aaron Hemens/Capital News)
126 new cases of COVID-19 in Interior Health over the weekend

There are 22 individuals hospitalized due to the virus, and 13 in intensive care

RCMP vest
Penticton beach brawl results in one arrest but no charges

People took to social media after a fight broke out at the fire pits at Okanagan Lake Saturday

Vernon local Ryan Lazar – who specializes in 2D background design and 3D animation – is ready to start his career after a tough yet rewarding two years of studies. (Contributed)
Okanagan College students get animated at graduation

‘The pandemic has resulted in more video consumption and the animation industry is so hot right now because of it’

Road work is underway in Penticton so traffic controllers are asking drivers to be aware. (Submitted)
Message to Penticton drivers: Slow down and pay attention in Cone Zones

Over the last 10 years in B.C., 12 roadside workers died and 207 were injured

Meghan Thompson and her daughter Kennedy Lanteigne were awarded bravery awards on Saturday for helping to save the life of a baby drowning off a Naramata beach last June. (Submitted)
Penticton mom and daughter receive bravery awards for saving baby from drowning

Off duty Penticton fire captain also awarded for saving the boy’s life last summer in Naramata

An avalanche near Highway 1 in Glacier National Park. Avalanche Canada will benefit from a $10 million grant from the B.C. government. (Photo by Parks Canada)
Avalanche Canada receives $10-million grant from B.C. government

Long sought-after funds to bolster organization’s important work

Barriere RCMP nabbed two suspects who were allegedly breaking into cabins in McLure. (File photo)
Thieves nabbed by Barriere Mounties during McLure break-ins

Police Service Dog Kody instrumental in making the arrest

(File photo)
Repeated cougar sighting on Okanagan Rail Trail

Plenty of bear sightings around the valley too

B.C. Health Minister Adrian Dix and provincial health officer Dr. Bonnie Henry update the province’s COVID-19 vaccine program, May 10, 2021. (B.C. government)
B.C.’s COVID-19 infection rate stays below 500 a day over weekend

14 more deaths, down to 350 in hospital as of Monday

Royal Bay Secondary School’s rainbow crosswalk was vandalized shortly after being painted but by Monday, coincidentally the International Day Against Homophobia, Transphobia and Biphobia, the crosswalk had been cleaned up and students had surrounded it with chalk messages of support and celebration. (Zoe Ducklow/News Staff)
B.C. high’s school’s pride crosswalk restored following ‘hateful’ graffiti attack

Hate terms, racial slur, phallic images spray-painted at Greater Victoria high school

Terrance Mack would have celebrated his 34th birthday on May 13, 2021. Mack’s family has identified him as the victim of a homicide in an apartment on Third Avenue in Port Alberni sometime in April. (SUBMITTED PHOTO)
Family identifies Ucluelet man as victim of Vancouver Island homicide

Terrance Mack being remembered as ‘kind, gentle’ man

A single motorcycle parked outside of the Kelowna Hells Angels clubhouse at 837 Ellis Street on July 9, 2020. (Michael Rodriguez - Capital News)
Kelowna Hells Angels prospect sentenced to 9 months in jail for aggravated assault

Colin Michael Bayley pleaded guilty to the downtown Kelowna assault earlier this month

Salmon Arm RCMP seize a handgun, drugs and cash at a Silver Creek property on Friday, May 14, 2021. (File photo)
Police seize handgun, drugs and cash at a Shuswap property

Salmon Arm RCMP said warrant for Silver Creek revealed cannabis, possible cocaine, magic mushrooms

Vernon Search and Rescue, along with Shuswap members, rescued three kayakers near Lumby Sunday, May 16, 2021. (VSAR Instagram)
3 kayakers rescued in North Okanagan

Shuswap, Vernon search and rescue teams make swift-water rescue Sunday

Most Read